The introduction of angiotensin-converting enzyme inhibitors for the treatment of hypertension and heart failure is probably the most important advance in cardiovascular pharmacofherapy in the last few decades. Although the role of the renin-angiotensin systemin cardiovascular diseases had been investigated extensively for more than 70 yr, the therapeutic application of this knowledge became possible only [...]
(British Approved Name, US Adopted Name, rINN) Drug Nomenclature International Nonproprietary Names (INNs) in main languages (French, Latin, Russian, and Spanish): BAN: Trandolapril INN: Trandolapril [rINN (es)] INN: Trandolaprilum [rINN (la)] Chemical name: Ethyl (2S,3aR,7aS)-1-{(S)-N-[(S)-1-carboxy-3-phenylpropyl]alanyl}hexahydro-2-indolinecarboxylate; (2S,3aR,7aS)-1-{N-[(S)-1-Ethoxycarbonyl-3-phenylpropyl]-l-alanyl}perhydroindole-2-carboxylic acid CAS: 87679-37-6 Read code: y01fQ Pharmacopoeias. In Europe. European Pharmacopoeia, 6th ed., 2008 and Supplements 6.1 and 6.2 [...]
Spirapril Hydrochloride (British Approved Name Modified, US Adopted Name, rINNM) Drug Nomenclature INNs in main languages (French, Latin, Russian, and Spanish): BAN: Spirapril Hydrochloride [BANM] INN: Spirapril Hydrochloride [rINNM (en)] INN: Spirapril, Chlorhydrate de [rINNM (fr)] INN: Спираприла Гидрохлорид [rINNM (ru)] Molecular formula: C22H30N2O5S2,HCl =503.1 ATC code: C09AA11 Pharmacopoeias. Europe includes the monohydrate. European Pharmacopoeia, [...]
