Patients with renal disease frequently have increased blood volume and increased peripheral vascular resistance. Excess blood volume is more common in glomerular diseases. Table Considerations for Initial Therapy in Patients with Renal Disease Pathophysiology Desirable pharmacologic approach” Increased blood volume (common in glomerular diseases) Reduce blood volume (loop diuretic, avoid hydrochlorothiazide if creatinine >2.0). Decreased [...]
Setting Targets Guidelines on when to start antihypertensive treatment have been published recently. The Sixth Joint National Committee on the Prevention, Detection, Evaluation and Treatment of High Blood Pressure (JNC VI) and the World Health Organization — International Society of Hypertension have provided very similar criteria to assist decision making. Table Risk Stratification and Treatment [...]
Choosing the best drug for a particular patient Whichever approach you use in beginning (or changing) antihypertensive therapy, you should evaluate your patient for characteristics that will predict a favorable or unfavorable response (Table 2). Table 2. Factors To Consider When Choosing An Antihypertensive Agent Dosing Frequency Quality Of Life Cost Possibility Of Pregnancy Age [...]
